Our sponsors
Team 06 is based on the complementary expertise contributed by a group (JS Silvestre) experienced in deciphering of signaling pathways involved in post-ischemic tissue remodeling and a group (P Menasché), with a long–standing experience in the preclinical, translational and clinical aspects of stem cell research. Team 06 forms an ideal platform of expertise and technical know-how, extending from the basic features of cell injury, regeneration and remodeling to the clinical applications of regenerative therapies complying with the increasingly stringent regulatory requirements. The team spans a fully integrated spectrum encompassing basic, preclinical and translational research ranging from the mechanisms of post-ischemic tissue remodeling and regeneration at the molecular level to the development of therapeutic strategies to mimic and boost these processes. The overall objective is thus to contribute to the burgeoning field of regenerative medicine where involved disciplines (cell biology, tissue engineering, immunology, regulation) are often partitioned by a cross-fertilization of expertise located on the same site and allow to both improve basic knowledge and clinical applications. As such, our research is targeted to scientists, clinicians, students, but ultimately to patients who are in need for these novel biologics-based therapeutic approaches, with the premise that implementation of these therapies cannot be truly relevant if it is not built on a robust understanding of the underlying mechanistic events.
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Key Words: Cardiovascular, Regenerative medicine, Myocardial Infarction, Heart failure, Inflammation, Stem Cells |